Zhe Wang Selected Research

Ketosis

5/2022	Overactivation of hepatic mechanistic target of rapamycin kinase complex 1 (mTORC1) is associated with low transcriptional activity of transcription factor EB and lysosomal dysfunction in dairy cows with clinical ketosis.
3/2022	Free fatty acids promote degranulation of azurophil granules in neutrophils by inducing production of NADPH oxidase-derived reactive oxygen species in cows with subclinical ketosis.
1/2022	Activation of Transcription Factor EB Is Associated With Adipose Tissue Lipolysis in Dairy Cows With Subclinical Ketosis.
12/2021	Sirtuin 3 inhibits nuclear factor-κB signaling activated by a fatty acid challenge in bovine mammary epithelial cells.
11/2021	Free fatty acids impair autophagic activity and activate nuclear factor kappa B signaling and NLR family pyrin domain containing 3 inflammasome in calf hepatocytes.
6/2021	Enhanced mitochondrial dysfunction and oxidative stress in the mammary gland of cows with clinical ketosis.
5/2021	Inhibition of cell death inducing DNA fragmentation factor-α-like effector c (CIDEC) by tumor necrosis factor-α induces lipolysis and inflammation in calf adipocytes.
1/2020	Non-esterified Fatty Acid Induce Dairy Cow Hepatocytes Apoptosis via the Mitochondria-Mediated ROS-JNK/ERK Signaling Pathway.
2/2019	The effects of non-esterified fatty acids and β-hydroxybutyrate on the hepatic CYP2E1 in cows with clinical ketosis.
2/2019	Expression patterns of hepatic genes involved in lipid metabolism in cows with subclinical or clinical ketosis.

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Zhe Wang Research Topics

Disease

296	Neoplasms (Cancer) 08/2022 - 03/2002
66	Inflammation (Inflammations) 08/2022 - 12/2009
48	Neoplasm Metastasis (Metastasis) 08/2022 - 03/2002
48	Breast Neoplasms (Breast Cancer) 07/2022 - 04/2004
41	Infections 12/2022 - 07/2002
33	Alzheimer Disease (Alzheimer's Disease) 08/2022 - 05/2010
27	Ketosis 05/2022 - 03/2008
25	Stomach Neoplasms (Stomach Cancer) 05/2022 - 07/2013
25	Acquired Immunodeficiency Syndrome (AIDS) 01/2017 - 02/2003
24	Carcinogenesis 06/2022 - 03/2007
23	Hypoxia (Hypoxemia) 07/2022 - 09/2006
23	Fatty Liver 02/2022 - 07/2009
22	Colorectal Neoplasms (Colorectal Cancer) 05/2021 - 07/2007
22	Hepatocellular Carcinoma (Hepatoma) 02/2021 - 07/2004
21	Carcinoma (Carcinomatosis) 05/2021 - 07/2013
17	Insulin Resistance 08/2022 - 07/2009
15	Fibrosis (Cirrhosis) 08/2022 - 01/2013
15	Tuberculosis (Tuberculoses) 11/2021 - 02/2011
14	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 04/2022 - 04/2010
14	Osteosarcoma (Osteogenic Sarcoma) 01/2021 - 09/2012
13	Spinal Cord Injuries (Spinal Cord Injury) 12/2022 - 10/2016
13	Lung Neoplasms (Lung Cancer) 01/2022 - 08/2009
13	Type 2 Diabetes Mellitus (MODY) 01/2022 - 11/2014
13	Wounds and Injuries (Trauma) 11/2021 - 02/2013
12	Colonic Neoplasms (Colon Cancer) 06/2022 - 01/2016
12	Hemorrhage 01/2022 - 10/2015
11	Disease Progression 12/2022 - 10/2011
11	Ovarian Neoplasms (Ovarian Cancer) 01/2022 - 03/2013
11	Glioma (Gliomas) 01/2022 - 06/2011
10	COVID-19 12/2022 - 01/2020
10	Cognitive Dysfunction 03/2022 - 07/2015
10	Osteoporosis 01/2022 - 01/2013
10	Stroke (Strokes) 12/2021 - 10/2014
10	Autoimmune Diseases (Autoimmune Disease) 10/2021 - 04/2008
10	Myocardial Infarction 08/2021 - 01/2013
10	Pain (Aches) 02/2021 - 12/2009
10	Prostatic Neoplasms (Prostate Cancer) 12/2019 - 03/2007
9	Atherosclerosis 06/2022 - 11/2013
9	Non-alcoholic Fatty Liver Disease 06/2022 - 01/2016
9	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2022 - 02/2015
9	Thrombosis (Thrombus) 01/2022 - 12/2014
9	HIV Infections (HIV Infection) 12/2021 - 03/2006
9	Neuroinflammatory Diseases 11/2021 - 10/2014
9	Lymphoma (Lymphomas) 09/2021 - 07/2007
8	Necrosis 01/2022 - 11/2010
8	Osteoarthritis 01/2022 - 03/2011
8	Body Weight (Weight, Body) 09/2021 - 12/2014
8	Amyloid Plaque 03/2020 - 06/2013
8	Sepsis (Septicemia) 01/2020 - 01/2014

Drug/Important Bio-Agent (IBA)

107	Proteins (Proteins, Gene)FDA Link 06/2022 - 07/2007
88	Pharmaceutical PreparationsIBA 06/2022 - 04/2004
34	Biomarkers (Surrogate Marker)IBA 06/2022 - 11/2014
34	MicroRNAs (MicroRNA)IBA 01/2022 - 08/2011
33	Messenger RNA (mRNA)IBA 08/2022 - 03/2005
30	Biological ProductsIBA 07/2022 - 07/2007
29	Glucose (Dextrose)FDA LinkGeneric 07/2022 - 07/2009
26	CytokinesIBA 01/2022 - 01/2012
25	EnzymesIBA 03/2022 - 01/2008
24	RNA (Ribonucleic Acid)IBA 01/2022 - 03/2010
23	Fatty Acids (Saturated Fatty Acids)IBA 08/2022 - 01/2011
21	LipidsIBA 01/2022 - 09/2011
19	Nonesterified Fatty Acids (NEFA)IBA 08/2022 - 01/2011
19	Therapeutic UsesIBA 06/2022 - 07/2004
17	LigandsIBA 01/2022 - 03/2007
16	Protein Kinases (Protein Kinase)IBA 12/2021 - 12/2006
15	Peptides (Polypeptides)IBA 01/2022 - 05/2013
15	LipopolysaccharidesIBA 12/2020 - 01/2014
14	AntigensIBA 11/2022 - 06/2005
14	Transcription Factors (Transcription Factor)IBA 06/2022 - 08/2010
14	Long Noncoding RNAIBA 03/2022 - 12/2017
14	Interleukin-6 (Interleukin 6)IBA 01/2022 - 02/2012
13	Indicators and Reagents (Reagents)IBA 12/2022 - 03/2010
12	Phosphotransferases (Kinase)IBA 08/2022 - 01/2014
12	Small Interfering RNA (siRNA)IBA 01/2022 - 04/2004
11	Insulin (Novolin)FDA Link 08/2022 - 07/2009
11	Amyloid (Amyloid Fibrils)IBA 04/2022 - 05/2010
11	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 07/2002
10	C-Reactive ProteinIBA 12/2022 - 02/2011
10	Cyclic PeptidesIBA 06/2022 - 08/2015
10	ChemokinesIBA 01/2022 - 02/2003
10	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022 - 07/2004
9	AntibodiesIBA 12/2022 - 08/2010
9	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2022 - 04/2016
9	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 08/2002
9	Estrogen ReceptorsIBA 07/2021 - 01/2007
8	Hormones (Hormone)IBA 10/2022 - 08/2012
8	IntegrinsIBA 05/2022 - 05/2009
8	Triglycerides (Triacylglycerol)IBA 02/2022 - 07/2009
8	AntioxidantsIBA 01/2022 - 04/2016
8	AnticoagulantsIBA 01/2022 - 11/2016
8	Matrix Metalloproteinases (MMPs)IBA 11/2021 - 10/2008

Therapy/Procedure

139	Therapeutics 12/2022 - 07/2005
42	Drug Therapy (Chemotherapy) 05/2022 - 06/2011
22	Radiotherapy 01/2022 - 01/2008
15	Chinese Traditional Medicine (Traditional Chinese Medicine) 05/2022 - 10/2007
14	Immunotherapy 04/2021 - 06/2015
11	Stents 01/2022 - 01/2018
10	Transplantation 01/2021 - 08/2007
8	Low-Level Light Therapy (LLLT) 12/2022 - 01/2017
8	Precision Medicine 01/2021 - 06/2013